Mild traumatic brain injury (mTBI), including sport-related concussion, has become a major health issue. Nearly 10% of mTBI patients (aged 0-18 years) are symptomatic with post-concussion syndrome (PCS) three months after injury. Persistent post-concussion symptoms often result in significant disability and family burden. However, the biological explanation for these prolonged PCS symptoms remains unclear.

Practice guidelines recommend that shared decision making should be used to engage patients and their families in discussions about care that is congruent with their values...